Tea And Sweat: A New Antiaging Strategy

February 24, 2009 by  
Filed under All, Science, Tea

Japanese researchers explored the effect of tea catechins and
regular exercise and the aging associated declining physical
performance in mice. The endurance capacity of mice as measured by
running time decreased by 17% in control mice, while those fed green
tea catechins (0.35%) suffered no decline in endurance. The authors
concluded “long-term intake of catechins, together with habitual
exercise, is beneficial for suppressing the age-related decline in
physical performance and energy metabolism, and these effects are due,
at least in part, to improved mitochondrial function in skeletal
muscle.”

Tea catechin ingestion combined with habitual exercise suppresses
the aging-associated decline in physical performance in
senescence-accelerated mice.

Am J Physiol Regul Integr Comp Physiol. 2008 May 14. Murase T, Haramizu S, Ota N, Hase T.

Catechins, which are abundant in green tea, possess a variety of
biologic actions, and their clinical application has been extensively
investigated. In this study, we examined the effects of tea catechins
and regular exercise on the aging-associated decline in physical
performance in senescence-accelerated prone mice (SAMP1) and
age-matched senescence-accelerated resistant mice (SAMR1). The
endurance capacity of SAMR1 mice, measured as the running time to
exhaustion, tended to increase over the 8-week experimental period,
whereas that of SAMP1 mice decreased by 17%. On the other hand, the
endurance capacity of SAMP1 mice fed 0.35% (w/w) catechins remained at
the initial level and was significantly higher than that of SAMP1 mice
not fed catechins. In SAMP1 mice fed catechins and given exercise,
oxygen consumption was significantly increased, and there was an
increase in skeletal muscle fatty acid beta-oxidation. The mRNA levels
of mitochondria-related molecules, such as peroxisome
proliferator-activated receptor-gamma coactivator-1, cytochrome c
oxidase-II, III, and IV in skeletal muscle were also higher in SAMP1
mice given both catechins and exercise. Moreover, oxidative stress
measured as thiobarbituric reactive substances was lower in SAMP1
groups fed catechins than in the SAMP1 control group. These results
suggest that long-term intake of catechins, together with habitual
exercise, is beneficial for suppressing the aging-related decline in
physical performance and energy metabolism, and that these effects are
due, at least in part, to improved mitochondrial function in skeletal
muscle. Key words: energy metabolism, exercise, green tea,
mitochondria, oxidative stress.

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