New research from Korea shows that EGCG selectively suppressed keloid fibroblast proliferation and migration compared to its effect on normal fibroblast proliferation and migration. Keloids are common benign skin tumors, characterized by collagen accumulation and hyperproliferation of fibroblasts.
Author Archive | Rob McCaleb
Green tea polyphenols have been reported to preserve tissues such as blood vessels, corneas, nerves, islet cells, articular cartilage, and myocardium. Research in Japan examined the effects of EGCG on skin preservation. Utilizing epidermal and dermal skin cells in culture, the researchers report that the tea polyphenol helped to preserve the skin cells for up […]
Scientists in Taiwan studied the effect of green tea extract on 78 obese women aged 16 to 60 years. They found no significant improvement in body weight, body mass index and weight circumflex. There were significant improvements in LDL cholesterol and triglyceride.
Japanese researchers explored the effect of tea catechins and regular exercise and the aging associated declining physical performance in mice. The endurance capacity of mice as measured by running time decreased by 17% in control mice, while those fed green tea catechins (0.35%) suffered no decline in endurance. The authors concluded “long-term intake of catechins, […]
Just to keep things in perspective, the previous item about green tea extracts potentially causing liver problems must be balanced against research showing that green tea is protective against liver disease. Chinese researchers a value weighted interventional and observational studies in both Western countries and in China published between 1989 and 2007. They found “a […]
Green tea is the fourth most commonly used dietary supplement in the United States. After the publication of adverse event case reports involving green tea products and potential liver toxicity, the US Pharmacopeia reviewed safety information for green tea products. 216 case reports on green tea products were analyzed including 34 reports concerning liver damage. […]
The green tea flavonoid EGCG has potential therapeutic value for treatment to for HIV-1 infection EGCG binds to the CD4 molecule on T-cells according to research conducted in 2006. “We have demonstrated clear evidence of high affinity binding of EGCG to the CD4 molecule. EGCG has potential use as an adjunctive treatment in HIV-1 infection.”
Recent research published in the American Journal of Physiology Endocrinology And Metabolism describes wide-ranging cardiovascular protective functions of a green tea polyphenol, EGCG. EGCG improved endothelial function and insulin sensitivity, reduced blood pressure and protected against myocardial ischemia and reperfusion injury. The addition of improvements in insulin sensitivity to the cardiovascular benefits indicates the benefit […]
In studies conducted on human skin, green tea polyphenols prevented ultraviolet (UVB) induced chemical changes in the skin, which are considered to be mediators of UVB induced immunosuppression and skin cancer induction. GTP treated humans can prevented penetration of UV radiation, and protected against UVB-induced local as well as systemic immune suppression in laboratory animals. […]
The incidence of late onset breast cancer has been increasing dramatically in the United States. Since genetic factors are believed to result primarily in early onset cases, accumulation of environmental toxins has been proposed as one factor in the increased incidence. Research reported in the Journal of Nutrition demonstrates that EGCG and protect mice against […]