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Rob McCaleb, HRF President

Rob’s Bio

Tea And Sweat: A New Antiaging Strategy

Japanese researchers explored the effect of tea catechins and regular exercise and the aging associated declining physical performance in mice. The endurance capacity of mice as measured by running time decreased by 17% in control mice, while those fed green tea catechins (0.35%) suffered no decline in endurance. The authors concluded “long-term intake of catechins, […]

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Green Tea Consumption And Liver Disease

Just to keep things in perspective, the previous item about green tea extracts potentially causing liver problems must be balanced against research showing that green tea is protective against liver disease. Chinese researchers a value weighted interventional and observational studies in both Western countries and in China published between 1989 and 2007. They found “a […]

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USP Investigates Safety Of Green Tea Extracts

Green tea is the fourth most commonly used dietary supplement in the United States. After the publication of adverse event case reports involving green tea products and potential liver toxicity, the US Pharmacopeia reviewed safety information for green tea products. 216 case reports on green tea products were analyzed including 34 reports concerning liver damage. […]

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Green Tea for HIV Treatment?

The green tea flavonoid EGCG has potential therapeutic value for treatment to for HIV-1 infection EGCG binds to the CD4 molecule on T-cells according to research conducted in 2006. “We have demonstrated clear evidence of high affinity binding of EGCG to the CD4 molecule. EGCG has potential use as an adjunctive treatment in HIV-1 infection.” […]

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Cardiovascular Benefits of EGCG

Recent research published in the American Journal of Physiology Endocrinology And Metabolism describes wide-ranging cardiovascular protective functions of a green tea polyphenol, EGCG. EGCG improved endothelial function and insulin sensitivity, reduced blood pressure and protected against myocardial ischemia and reperfusion injury. The addition of improvements in insulin sensitivity to the cardiovascular benefits indicates the benefit […]

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Green Tea Polyphenols (GTP) Against Skin Cancer

In studies conducted on human skin, green tea polyphenols prevented ultraviolet (UVB) induced chemical changes in the skin, which are considered to be mediators of UVB induced immunosuppression and skin cancer induction. GTP treated humans can prevented penetration of UV radiation, and protected against UVB-induced local as well as systemic immune suppression in laboratory animals. […]

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Green Tea Polyphenol EGCG Inhibits Breast Cancer

The incidence of late onset breast cancer has been increasing dramatically in the United States. Since genetic factors are believed to result primarily in early onset cases, accumulation of environmental toxins has been proposed as one factor in the increased incidence. Research reported in the Journal of Nutrition demonstrates that EGCG and protect mice against […]

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Green Tea And Thermogenesis

The thermogenic effect of tea is generally attributed to its caffeine content. An article in Alternative Medicine Review reports that green tea extract stimulates brown adipose tissue thermogenesis to an extent which is much greater than can be attributed to its caffeine content alone. Since polyphenols and caffeine inhibit different cellular reactions involving norepinephrine, the […]

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Green Tea Anti-Inflammatory

Green tea polyphenols such as EGCG have potent anti-inflammatory properties. Prior research had shown that EGCG inhibits tumor necrosis factor through a mechanism that was thought to have implications for inflammation generally. Epidemiological studies link regular consumption of tea with decreased cancer risk and a reduction in mortality during the 12 month period following a […]

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Potent Suppressive Effect Of Green Tea Polyphenols On Tobacco Induced Mutagenicity

Research from India reported in Phytomedicine explored the anti-mutagenic activity of green tea. Using standard mutagenicity assays, a team of research demonstrated that green tea polyphenols could inhibit the mutagenicity of tobacco in a concentration-dependent manner. The polyphenols were also found to inhibit urinary mutagenicity in rats induced by tobacco extract. Thus “green tea has […]

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