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Andrographis herb combination effective against cold and flu

Two consecutive randomized, double-blind clinical trials concluded that a fixed combination of Andrographis paniculata and Siberian ginseng (eleuthero, Eleutherococcus senticosus) was significantly more effective than placebo in relieving symptoms of cold or flu. In the first trial (a pilot study of 46 subjects) the total symptom score showed a tendency toward improvement, while in the second (a larger, phase III clinical study involving 179 participants), highly significant improvement was seen in both total symptom and total diagnosis scores in people taking the herbal formula. For the pilot trial, subjects were treated for a minimum of three and a maximum of eight days; in the phase III trial, subjects took the herbal formula for exactly three days. Results were assessed by both participants and physicians. In both studies, throat symptoms demonstrated the most significant improvement. Melchior J, Spasov AA, Ostrovkij OV, et al. Double-blind, placebo-controlled pilot and phase III study of activity of standardized Andrographis paniculata Herba Nees extract fixed combination (Kan jang) in the treatment of uncomplicated upper-respiratory tract infection. Phytomedicine 2000; 7(5): 341-350.

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