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Large study concludes ginkgo is ineffective in tinnitus

A 12-week, double-blind, placebo-controlled trial involving 978 people (489 matched pairs) concluded that Ginkgo biloba extract was no more effective than placebo in improving symptoms of tinnitus (ringing in the ears). Effects were assessed via questionnaires at baseline, after four and 12 weeks of treatment, and again two weeks after treatment ended. In addition to questions about the severity of tinnitus, the questionnaires included items on symptoms of cerebral insufficiency (inadequate blood flow to the brain) other than tinnitus. The researchers concluded that ginkgo "seems to be ineffective in treating tinnitus alone, but it may be effective in treating tinnitus in patients who also have other symptoms of cerebral insufficiency." The ginkgo preparation used in the study was the standardized extract LI 1370, manufactured by Berlin-based Lichtwer Pharma. Drew S, Davies E. Effectiveness of Ginkgo biloba in treating tinnitus: double blind, placebo controlled trial. British Medical Journal 2001; 322:73-75.

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