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Bone density and soy isoflavones

This review article summarizes the current research into the potential positive effects of soy consumption on bone health in humans. Soy contains a number of isoflavones; genistein and daidzein have been particularly well studied. Animal studies have provided convincing evidence of improved bone mass following soy consumption. The only completed study investigating effects in humans researched the effects of soy protein on bone mineral density (BMD) in post-menopausal women and revealed significant improvement in lumbar vertebral BMD, but not in femoral or total body BMD. According to the authors, no epidemiological analyses have been noted in the scientific literature. A review of laboratory studies is included in the article, with discussion of possible mechanisms of action of soy isoflavones in bone tissue.

Full article $20 - Review Order
Anderson J, Garner S. Effects of soy isoflavones on bone. Nutr Aspects Osteoporosis 1998; 172-179 (Proc. Symp. 1997)

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